A study to dtermine the use of serum biomarkers and thermography to doagnose bacterial infectioms in early post operative orthopedics patients
- Conditions
- Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- CTRI/2022/02/039996
- Lead Sponsor
- Science and Engineering Research Board SERB
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Case :Adult ( > 18 years)
1.Should have undergone an orthopaedic trauma surgery (with or without orthopaedic implants)
and should have developed clinical signs of surgical site infection, within three weeks (early in-fection) post-operatively.
2.Should have a positive microbial culture
3.Should be willing to participate in the study
Controls: Adult post-operative orthopaedic trauma patients with negative wound cultures and no cli-nico-radiological signs/symptoms of infection will be included as controls.
Exclusion Criteria
1.Children (<= 18 years)
2.Infections beyond 3 weeks.
3.Culture negative patients
4.Acute flare up of chronic infections
5.Patients in renal, hepatic or cardiac failure.
6.Patients with congenital or acquired immunodeficient states.
7.Patient not willing to give consent / participate in the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To develop a diagnostic tool for early detection of the surgical site infection with serological markers.Timepoint: 6-24 months
- Secondary Outcome Measures
Name Time Method to develop a new tool to predict and detect SSI at the early stage and an appropriate early intervention can be taken to prevent the fulminant infection.Timepoint: 18-24 months