A comparison of IL-6, IL-10, TNF-alpha serum level change between in total laparoscopic hysterectomy and myomectomy patient under total intravenous anesthesia (TIVA) using propofol and remimazolam
Not Applicable
Recruiting
- Conditions
- Neoplasms
- Registration Number
- KCT0007611
- Lead Sponsor
- Daegu Fatima Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 46
Inclusion Criteria
This study was conducted with patients aged 20 to 65 who underwent laparoscopic hysterectomy or laparoscopic myomectomy under general anesthesia with ASA score (American society of anesthesiology physical state score) I and II.
Exclusion Criteria
The following patients are excluded from the study. Immune system disorder and systemic disorder (systemic lupus erythematosus, rheumatoid arthritis, leukemia, etc.), patients with drug allergy, patients taking steroids such as oral contraceptives or taking them within 6 months, drug addiction or alcoholism , patients with neuropsychiatric disorders, pregnancy, patients with a body mass index (BMI) of 25 or higher
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Interleukin-6 ( IL-6 );Interleukin-10 ( IL-10 );tumor necrosis factor -alpha (TNF - a)
- Secondary Outcome Measures
Name Time Method hospitality stay ;Blood pressure, heart rate, saturation ;numeric rating sclae of operation site pain ; dose of opioid analgesics (fentanyl, oxycodone);postoperative nausea and vomiting