ocal excision with postoperative chemoradiotherapy for T1, T2 rectal cancer
Phase 2
- Conditions
- T1,T2 cancer of low rectum
- Registration Number
- JPRN-UMIN000011417
- Lead Sponsor
- ational Cancer Center Hospital East
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
Not provided
Exclusion Criteria
1. Pathological proven poorly or mucinous adenocarcinoma by biopsy 2. Clinical N positive 3. Distant metastasis 4. PS (ECOG) 2, 3, and 4 5. Without written informed consent 6. Pathological proven poorly or mucinous adenocarcinoma in resected specimen 7. Pathological positive surgical margins in resected specimen 8. Depth of m invasion, or sm-minute invasion without vessels invasion 9. Bone marrow dysfunction 10. Be certain or suspicious pregnant 11. Precious radiotherapy in abdomino-pelvic area 12. Unsuitable patients for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disease free survival at five years
- Secondary Outcome Measures
Name Time Method Overall survival at five years Local relapse-free survival Salvage treatment and prognosis Adverse events in chemoradiotherapy