A prospective cohort study of thrombosis and tissue factor in patients with pancreas or biliary tract cancer
- Conditions
- Patients with pancreas or biliary tract cancer who have not thrombosis
- Registration Number
- JPRN-UMIN000010910
- Lead Sponsor
- Kanagawa Cancer Center
- Brief Summary
Incidence of CAT was 6.6% in pancreatic cancer cohort. Plasma Tissue factor (TF) level was significant higher in patients with pancreatic cancer than that of healthy volunteers, even if patients did not show CAT. Positive and negative predictive value was 23.1% and 94.6% using 100 pg/mL of plasma TF level as a cut-off, which were better than d-dimer or khorana score.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 276
Not provided
Part I; 1)have the medical history of thromboembolism whithin 5 years or have thrombosis at the time of inclusion, 2)inappropriate to this this study judged by the investigator Part II; 1)have the medical history of thromboembolism whithin 5 years or have thrombosis at the time of inclusion, 2)allergy to the contrast enhancing media, 3)intake regularly anti-coagulant agent, 4)with obstrucive janudice or acute pancreatitis, 5)inappropriate to this this study judged by the investigator
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method