NCT02566629Unknown不适用
Microbiota Community of Irritable Bowel Syndrome in Episodes and Remission Phase
Shandong University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2015年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- microbiota community among IBS patients in episodes phase,remission phase and healthy controls
研究概览
简要总结
Analyze microbiota community of irritable bowel syndrome in episodes phase and remission phase.
详细描述
The pathophysiology of IBS is incompletely understood, it may involve an altered intestinal microbiota. Since the microflora composition of IBS is various in different studies, The investigators plan to compare the intestinal microbiota of IBS patients in episodes phase and remission phase with healthy controls,trying to find the difference.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •the presence of Rome III criteria for IBS ;
- •Patients scheduled for colonoscopy examination or having negative screening examinations
- •Aged between 18 and 65 years old
排除标准
- •Antibiotic, probiotic or laxative usage within 4 weeks.
- •organic gastrointestinal diseases
- •Severe systematic disease: diabetes mellitus, hepatic, renal or cardiac dysfunction, thyroid disease or tumor etc.
- •pregnancy or lactation.
- •previous major or complicated abdominal surgery.
- •severe endometriosis and dementia
结局指标
主要结局
microbiota community among IBS patients in episodes phase,remission phase and healthy controls
时间窗: 5 months
次要结局
- quality of life in IBS patients(5 months)
研究者
Yanqing Li
Vice president of Qilu Hospital
Shandong University
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Changes of Microbiota in Irritable Bowel Syndrome PatientsMucosa Associated Bacteria in Small IntestineNCT01679730Far Eastern Memorial Hospital40
已完成
不适用
Evaluation Study of the Intestinal Microbiota and Quality of Life in Patients Suffering From IBS Treated With BifidiceIrritable Bowel SyndromeNCT05663060Istituto Clinico Humanitas8
招募中
不适用
Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With ConstipationIrritable Bowel SyndromeNCT05803993Fondazione Policlinico Universitario Agostino Gemelli IRCCS35
招募中
不适用
Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome Without ConstipationIrritable Bowel SyndromeNCT05803980Fondazione Policlinico Universitario Agostino Gemelli IRCCS35
招募中
不适用
A Cohort Study of Intestinal Microbiota among IBS patients (CO-MIC study)IBS10017977NL-OMON33268Wageningen Universiteit200