A Cohort Study of Intestinal Microbiota among IBS patients (CO-MIC study)
Recruiting
- Conditions
- 10017977IBS
- Registration Number
- NL-OMON33268
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
* Aged 18 or older
* Subjects must be able to understand the written study information and must be able to sign an informed consent
* Subjects must be willing to collect faeces
* Specifically for IBS: Rome III Criteria
* Specifically for asymptomatic controls: no intestinal diseases in the colon
Exclusion Criteria
* Change in use of medication that may affect the intestinal microbiota, such as prebiotics, and laxatives
* Recent use of probiotics (for at least one month before collection of the fecal samples)
* Pre-exiting bowel diseases (such as inflammatory bowel disease or cancer)
* Pregnancy/breast feeding
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study outcome parameter is diversity and functionality of intestinal<br /><br>microbiota, which will be monitored every 1-2 months during a period of 6-12<br /><br>months. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Additional study parameters include quality of life, disease and treatment<br /><br>characteristics, and lifestyle factors including dietary intake, clinical<br /><br>patient history, family history, and demographics.</p><br>