A novel and minimally invasive surgery termed Percutaneous-transpedicular Injection of Polymethylmethacrylate into the Intervertebral vacuum space (PIPI) for chronic and disabling low back pain associated with de novo degenerative lumbar scoliosis in the elderly: a prospective single-center cohort study
- Conditions
- Degenerative lumbar scoliosis
- Registration Number
- JPRN-UMIN000016127
- Lead Sponsor
- JA Hiroshima General Hospital
- Brief Summary
1) The immediate and substantial relief of low back pain has been achieved after PIPI for at least two years. 2) Non-operative treatment had no efficacy on the treatment of low back pain. 3) Bone marrow edema significantly improved in the PIPI group but not in the non-operative group. 4) The degree of bone marrow edema was correlated with the strength of VAS and the degree of ODI.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 162
Not provided
1) Osteoporosis or lumbar vertebral density <70% of that of the young adult mean as determined by dual-energy x-ray absorptiometry 2) Infectious disease 3) Tumorous conditions of the spine 4) History of lumbar surgery 5) Leg length discrepancy due to hip or knee joint disease 6) LBP alleviated by facet joint anesthetic injections 7) Disoriented or did not complete the screening questionnaire
Study & Design
- Study Type
- Interventional,observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Visual analogue scale (VAS) for low back pain 2) Oswestry disability index 3) Bone marrow edema on MRI
- Secondary Outcome Measures
Name Time Method