The effect of N-acetylcysteine supplementation on cycling performance and adaptation to exercise in well-trained athletes

Phase 4

• Conditions: Exercise adaptation; Other - Conditions of unknown or disputed aetiology (such as chronic fatigue syndrome/myalgic encephalomyelitis)

• Registration Number: ACTRN12609000804280
• Lead Sponsor: niversity of Technology, Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-09-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

High level of physical fitness
Completed 10-15 h/wk physical training for at least 2 y in either cycling or triathlon

Exclusion Criteria

Regular antioxidant supplementation for previous 4 wks
Illness or injury which may be exacerbated through participation in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cycle ergometer performance time trial.[pre (day 1) and post (day 9) of each experimental period];Venous blood testing to determine changes total antioxidant status (TAS), glutathione/reduced glutathione ratio (GSSG:GSH), thiobarbituric acid-reactive substances (TBARS), interlukin-6 (IL-6), nuclear factor-kB and creatine kinase.[pre, immediately post, 2 h post and 24 h post each Cycle ergometer test]

Secondary Outcome Measures

Name	Time	Method
Training diaries and the Daily Analysis of Life Demands for Athletes[Completed on a daily basis during the experimental period]