NCT04512859Unknown不适用
Effect of Stellate Ganglion Block on Cerebral Vasospasm in Patients With Emergency Aneurysmal Subarachnoid Hemorrhage
Beijing Tiantan Hospital0 个研究点目标入组 160 人开始时间: 2020年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 160
- 主要终点
- The incidence of cerebral vasospasm
研究概览
简要总结
To investigate whether the stellate ganglion block is helpful in relieving cerebral vasospasm during aneurysmal coil embolism surgery. The effect was assessed by Transcranial Doppler (TCD).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1.Emergency patients with subarachnoid hemorrhage caused by ruptured aneurysm, aged 18-65 years;
- •ASA : II-IV grade, Hunt-Hess : I-III grade
- •For the first case, the operation time is within 24 hours. 4.After signing informed consent, underwent interventional intravascular embolization
排除标准
- •1. Patients with severe bleeding disorders;
- •Patients with trauma and local infection risk in the nerve block area;
- •Patients with previous aneurysm surgery and unruptured aneurysm;
- •Aneurysm located in middle cerebral artery;
- •Patients with unconsciousness cannot cooperate with the block operation;
- •Those with a history of mental illness and epilepsy;
- •Those who have a history of severe cardiovascular and cerebrovascular diseases and severe organ diseases;
结局指标
主要结局
The incidence of cerebral vasospasm
时间窗: Change from baseline at 5day,after subarachnoid hemorrhage
次要结局
未报告次要终点
研究者
Yuming Peng
Vice Professor
Beijing Tiantan Hospital
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