Colonoscopic Adenoma and Advanced Neoplasia Detection Rates According to Age
- Conditions
- Colon CancerAgeColonic PolypColonoscopyColon Adenoma
- Registration Number
- NCT03361904
- Lead Sponsor
- Société Française d'Endoscopie Digestive
- Brief Summary
Current recommendations for colonoscopy screening programs usually involve patients older than 50 years of age. However, little is known about polyp or adenoma detection rates under 50. We compared these detection rates according to age in a large series of patients in common practice.
Methods: All colonoscopies performed in 2016 in our unit were prospectively recorded. We determined adenoma detection rate (ADR), polyp detection rate (PDR), mean number of polyps (MNP), and advanced neoplasia detection rate (ANDR).
- Detailed Description
Patients All consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were: patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).
Data collection The following data have been prospectively collected: age, gender, indication for colonoscopy, preparation procedure and quality of the preparation (assessed by the Boston Bowel Preparation Scale; BBPS) \[19-20\], caecal intubation (yes/no), withdrawal time, number and size of polyps and polyp histopathology.
All clinical data were collected during the procedure by a nurse and an endoscopist on a dedicated software. The database was then supplemented by the Clinical Research Associate for histopathological data.
We determined adenoma detection rate (ADR; percentage of colonoscopies with at least one adenoma), polyp detection rate (PDR: percentage of colonoscopies with at least one polyp), mean number of polyps per colonoscopy (MNP), large polyp detection rate (LPDR; percentage of colonoscopies with at least one polyp of 1 cm or more) and advanced neoplasia detection rate (ANDR: percentage of colonoscopies with at least one advanced neoplastic lesion as defined below).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 6027
- All consecutive patients who were scheduled for colonoscopy were included.
- patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adenoma detection rate according to age during colonoscopy ADR \<30yo, in 30-34 yo, in 35-39yo, in 40-44yo, in 45-49yo, in 50-54yo, in 55-59yo, in 60-64yo, in 65-69 yo, in 70-74yo, in 75-79yo and \>79yo intervals
Advanced Neoplasia Detection rate according to age during colonoscopy ANDR \<30yo, in 30-34 yo, in 35-39yo, in 40-44yo, in 45-49yo, in 50-54yo, in 55-59yo, in 60-64yo, in 65-69 yo, in 70-74yo, in 75-79yo and \>79yo intervals
- Secondary Outcome Measures
Name Time Method Age during colonoscopy years old
Gender during colonoscopy Male or Female
Caecal intubation during colonoscopy Y/N
Indication for colonoscopy during colonoscopy pain / screening/ familial or personal history of polyp or cancer
quality of the preparation during colonoscopy Boston Bowel Preparation Scale Segment Score Description 0: unprepared colon segment with mucosa not senn due to solid stool that cannot be cleared
1. Portion of mucosa of the colon segment seen, but other areas of the colon segment are not well seen due to staining, residual stool, and/or opaque liquid
2. minor amount of residual staining, small fragments of stool, and/or opaque liquid, but mucosa of colon segments is seen well
3. entire mucosa of colon segment seen well, with no residual staining, small fragments of stool or opaque liquid
Total score is a summation of scores from three segments of the colon Score is from 0 to 9Withdrawal time during colonoscopy in seconds