Study to assess the optimum dose of intravenous adenosine in the assessment of fractional flow reserve - Pressure Wire Study

Central Manchester and Manchester Children's Hospital University NHS Trust0 个研究点目标入组 0 人开始时间: 2007年7月31日最近更新: 2019年11月25日

适应症

试验速览

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•Any patient listed for pressure wire study of a moderate coronary artery lesion
•Any patient attending for coronary angiography +/- proceed who is found to have a moderate lesion considered to require pressure wire assessment.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Any patient who is unable or unwilling to give full informed consent.
•Patients with a contraindication to the administration of adenosine:
•Patients with a history of allergy or previous adverse reaction to administration of adenosine
•Second or third degree AV block, sick sinus syndrome (except in patients with a permanent pacemaker)
•Long QT syndrome
•Wolff Parkinson White Syndrome
•Severe hypotension (SBP <90)
•Unstable angina not successfully stabilised with medical therapy
•Decompensated heart failure
•Severe asthma
•Patients taking dipyridamole
•Patients taking theophylline / aminophylline therapy

发起方

Central Manchester and Manchester Children's Hospital University NHS Trust