Skip to main content
MedPathMedPath Home
Clinical Trials/EUCTR2014-001948-37-GB
EUCTR2014-001948-37-GB
Active, not recruiting
Phase 1

Intramuscular oxytocics: A multi-centre randomised comparison study of intramuscular Carbetocin, Syntocinon and Syntometrine for the third stage of labour following vaginal birth - IMox study

orth Bristol NHS Trust0 sites6,285 target enrollmentSeptember 30, 2014
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
DrugsPabalSyntocinonSyntometrine

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Not specified
Sponsor
orth Bristol NHS Trust
Enrollment
6285
Status
Active, not recruiting
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
September 30, 2014
End Date
TBD
Last Updated
7 years ago
Study Type
Interventional clinical trial of medicinal product

Investigators

Sponsor
orth Bristol NHS Trust

Eligibility Criteria

Inclusion Criteria

  • •\- 18 years of age, or older, at time of delivery
  • •\- Singleton pregnancy
  • •\- Vaginal birth (spontaneous and instrumental)
  • •\- Any gestation
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range: 0
  • •F.1\.2 Adults (18\-64 years) yes
  • •F.1\.2\.1 Number of subjects for this age range 6285
  • •F.1\.3 Elderly (\>\=65 years) no
  • •F.1\.3\.1 Number of subjects for this age range 0

Exclusion Criteria

  • •\- Significant antepartum haemorrhage (\>50ml) or suspected or proven placenta abruption
  • •\- Maternal coagulation disorder
  • •\- Multiple pregnancy (twins or higher order)
  • •\- Intrauterine fetal death
  • •\- Patients who would decline blood products if required (ie: Jehovah's Witnesses \- clinicians may have a lower threshold for administering additional prophylactic uterotonic drugs to these patients)
  • •\- Known or suspected hypertensive disorders, including pre\-eclampsia, pregnancy induced hypertension, essential hypertension (even if blood pressure well controlled), and patients with hypertension in labour
  • •\- Patients with peripheral, hepatic or cardiac disease
  • •\- Patients with an allergy or hypersensitivity to any of the active ingredients in Carbetocin, Syntometrine or Syntocinon

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Not Applicable
A study comparing three medicines used for the active management of the third stage of labour (to help deliver the placenta after your baby has been born)Specialty: Reproductive health and childbirth, Primary sub-specialty: Reproductive and Sexual MedicineUKCRC code/ Disease: Reproductive Health and Childbirth/ Complications of labour and deliveryPregnancy and ChildbirthReproductive Health and Childbirth/ Complications of labour and delivery
ISRCTN10232550orth Bristol NHS Trust5,717
Not yet recruiting
Not Applicable
A randomised controlled trial of intravenous versus intramuscular oxytocin in the management of third stage of labor.
ACTRN12612000624886Khon Kaen Hospital450
Completed
Phase 1
Safety, blood levels and effects of N,N-dimethyltryptamine [DMT (SPL026)] in healthy participants that have taken psychedelic substances before (Part A) and in healthy participants with little to no psychedelic experience (Part B)Healthy volunteersNot Applicable
ISRCTN63723571Cybin UK Ltd14
Not yet recruiting
Phase 4
Comparison of the effectiveness of intramuscular olanzapine with intramuscular haloperidol for the treatment of agitation in patients with Bipolar DisorderBipolar disorder.Bipolar disorder
IRCT20230131057294N1niversity of social welfare and rehabilitation sciences40
Withdrawn
Phase 2
A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKAOsteoarthritis, Knee
NCT04493229Wake Forest University Health Sciences