NCT04436679已完成不适用
INTER-Regional COHORTE of Long Term Pancreatic Cancer Survivors
University Hospital, Lille1 个研究点 分布在 1 个国家目标入组 342 人开始时间: 2021年2月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 342
- 试验地点
- 1
- 主要终点
- Relationship between known prognostic histological markers of pancreatic adenocarcinoma and patient survival.
研究概览
简要总结
The study is particularly innovative as it will accurately analyze the microscopic characteristics of the stroma, tumor budding and mucin expression in adenocarcinomas of the pancreas, using a comparative approach of long-survivor/short-survival patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients > 18 years of age at diagnosis
- •Primary pancreatic cancer patients operated on in one of the 4 centres between 2001 and 2016
- •Histopathological diagnosis of excreto-pancreatic adenocarcinoma of the pancreas, ductal adenocarcinoma or classical adenocarcinoma
- •Tissue blocks (FFPE) available (tumour/healthy tissue)
- •Affiliated to a social security scheme
排除标准
- •Absence of Primary Cancer Tissue Blocks (PCTBs)
- •Paraffin block fixed in Bouin or AFA
- •Patient Refusal
- •Pancreatic cancer not corresponding to a conventional excretopancreatic adenocarcinoma such as: carcinoma on intraductal papillary mucinous neoplasm, endocrine tumor/carcinoma, acinar cell carcinoma, ...).
- •Patient died due to post-surgical complications (death within 30 days post-surgery).
- •Surgical resection of macroscopic R2 type.
结局指标
主要结局
Relationship between known prognostic histological markers of pancreatic adenocarcinoma and patient survival.
时间窗: at 2 years
Tissue analysis will be performed by conventional microscopy and will evaluate histological markers known in the literature to have a prognostic impact.
次要结局
- Relationship between newly described histological markers for pancreatic adenocarcinoma and patient survival.(at 2 years)
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Integrative Proteomic Characterization of Pancreatic Ductal AdenocarcinomaTumor Tissues and Non-tumor Tissues From PDAC Patients Were Used for Genomic and Transcriptome Sequencing Analysis and Proteomics and Phosphorylated ProteomicsNCT04525209Ruijin Hospital200
招募中
不适用
Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function TestsPancreatic Exocrine InsufficiencyCommunity PopulationsFecal Elastase-1 TestDiabetes MellitusChronic PancreatitisNCT06006312Changhai Hospital2,400
已完成
1 期
Human Islet Transplantation in Brittle Type 1 Diabetes Mellitus. The GRAGIL 2 Study.Type 1 Diabetes MellitusNCT00321256University Hospital, Grenoble22
进行中（未招募）
不适用
Research of the Application of Pancreatic Cancer Screening Artificial Intelligence Model "PANDAPro"Pancreatic CancerNCT06643715Zhejiang University100,000
终止
1 期
Transplantation of Pancreatic Islets in Patients With Type 1 Diabetes Mellitus and Functional Kidney GraftType 1 Diabetes MellitusNCT00639600University Hospital, Grenoble21