Effect of vaginal contraction exercise in bladder control in women with multiple sclerosis and neurological disease caused by the virus HTLV1

Not Applicable

Recruiting

• Conditions: Z22.6; G95.8; Multiple sclerosis and Tropical spastic paraparesis in the carrier of T-lymphotropic virus type 1 infection [HTLV-1]; C10.114.375.500; C02.782.815.200.470.710

• Registration Number: RBR-2hpkp3
• Lead Sponsor: niversidade Federal de Mato Grosso do Sul

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-07-19
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women with diagnosis defined in Multiple Sclerosis, in the relapsing remitting form
And with the disease stabilized for at least four months, EDSS score less than or equal to 6.5. Or women with a diagnosis defined in HAM / TSP, with more than 18 years of age with HTLV - 1 positive ELISA and confirmed by Western blot (HTLV Blot 2.4), with urological and neurological evaluation, Osame Motor Scale dysfunction OMSS) and score in the lower EDSS equal to 6.5.
Aged over 18years, cognitive ability to respond to evaluation questionnaires and treatment protocol, presenting symptoms of urinary dysfunction for at least six months (at least three of the following: urgency,
Urge incontinence, high voiding frequency, nocturia and nocturnal enuresis), with no history of previous treatment with pelvic floor exercises, those that will not present genital prolapses
Or history of previous gynecological surgeries that are not pregnant, with no history of vaginal delivery or cesarean section within a period of less than six months prior to the start of the study, as well as those who will be out of menopause and without urinary infection excluded by laboratory examination.

Exclusion Criteria

Pregnant women with Diabetes mellitus, indigenous ethnicity and or quilombola, under the age of 18. Women who present exacerbation of symptoms or outbreak during the course of treatment, those who can not attend the treatment and refuse to perform the proposed treatment or voluntarily give up.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A reduction of at least 50% of the urinary symptoms evaluated by the specific questionnaires is expected and an at least 30% increase in the strength and contractility of the pelvic floor evaluated by electromyography and perfect scale, 1 week after the end of intervention in the women treated by electrostimulation and supervised exercises when compared to the control group.<br>;Improvement of at least 30% in quality of life indices evaluated through the Qualiveen questionnaire 1 week after the end of intervention in the group of women submitted to exercise therapy and electrostimulation of the pelvic floor when compared to the control group.

Secondary Outcome Measures

Name	Time	Method
Improvement of at least 30% in sexual function indexes evaluated through the FSFI questionnaire One week after the end of the intervention in the group of women submitted to exercise therapy and electrostimulation of the pelvic floor when compared to the control group.;It expects a benefit in all women involved in the study in view that they will receive conventional medical treatment and health education.<br>