跳至主要内容
临床试验/NCT06365294
NCT06365294已完成不适用

Rescue Extracranial Vertebral Stenting in Tandem Occlusions

Dr. Cuong Tran Chi2 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2020年12月31日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
9
试验地点
2
主要终点
The good 3-month outcome rate

研究概览

简要总结

The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. The investigators reported whether the additional rescue extracranial stenting improved clinical outcome by modified Rankin Scale (mRS) score within 3 months after the procedure

详细描述

Acute vertebrobasilar artery occlusion is one of the cerebrovascular diseases with high disability and mortality rates. Although mechanical thrombectomy has recently been demonstrated an effective treatment for large vessel occlusions of posterior circulation, the treatment strategies depending on the specific pathophysiology. Tandem occlusion in posterior circulation is less frequently than in anterior one, comprises severe stenosis or occlusion of the extracranial vertebral artery ipsilateral to its intracranial and basilar occlusion. The recent studies showed the benefit of the "distal-to-proximal" approach, there were many tecniques to achieved the successful recanalization. Besides, the use of Dotter technique allowed 8F guiding catheter to cross the extracranial lesions easily and save the procedural time. However, the Diagnosis 5F-Dotter, like the Dilator-Dotter, has not been mentioned in previous studies. Therefore, the aim of the our study was to assess the improvement of outcomes at 3 months posttreatment in patients receiving rescue extracranial vertebral stenting

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age > 18 years old
  • Onset to treatment time < 24 hours
  • NIHSS > 5
  • pc-ASPECTS ≥ 5

排除标准

  • Premorbid mRS > 2
  • Extensive, bilateral brain-stem infarction on neuroimaging
  • Cerebellar mass effect on neuroimaging
  • Loss to follow-up

结局指标

主要结局

The good 3-month outcome rate

时间窗: 3 months

The good 3-month outcome rate was accessed by modified Rankin Score (mRS ≤ 2).

次要结局

未报告次要终点

研究者

发起方
Dr. Cuong Tran Chi
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Dr. Cuong Tran Chi

Director - Doctor

Can Tho Stroke International Services Hospital

研究点 (2)

Loading locations...

相似试验