CTRI/2025/06/089863尚未招募不适用
Co-existence of viral infections in Oral Leukoplakia: A Clinical and Molecular Study
Dr. D. Y. Patil Dental College and Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年7月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Expression of viral oncoproteins (e.g., HPV-E6, EBV-LMP1) via IHC
研究概览
简要总结
This study will check for viral infections in people who have oral white patches (oral leukoplakia), which can turn into cancer. We will collect samples like saliva and blood, and analyze them using laboratory tests to detect viruses. The goal is to find whether viruses like HPV or EBV are linked to disease severity.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged 18 years or older with clinically diagnosed Oral Leukoplakia (OL).
- •Willingness to provide informed consent and tissue samples for molecular and histopathological analysis.
排除标准
- •Presence of other/co-existing oral potentially malignant disorders or malignancies.
- •Immunocompromised individuals.
结局指标
主要结局
Expression of viral oncoproteins (e.g., HPV-E6, EBV-LMP1) via IHC
时间窗: baseline
次要结局
- Prevalence of HPV, EBV, & HSV infections in OL(baseline)
- Correlation of viral presence with histopathological grade of dysplasia(baseline)
研究者
AKASH DATTATRAY BADE
Dr. D. Y. Patil Dental College and Hospital
研究点 (1)
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