The Relationship of Cognitive Functions to Physical and Personal Factors in Patients With Multiple Sclerosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Gazi University
- Enrollment
- 137
- Locations
- 1
- Primary Endpoint
- cognitive function
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Approximately 65% of multiple sclerosis (MS) patients appear to have problems in their cognitive function. Long-term memory is one of the most frequently affected functions in MS patients. Many factors play a role in the deterioration of cognitive functions because of many symptoms of MS.
The aim of this study is to investigate the relationship of cognitive function with physical factors such as balance, functional exercise capacity and personal factors such as fatigue level, mood, sleep quality in patients with MS.
Detailed Description
Patients with MS between 0-5,5 score according to the Extended Disability Status Scale (EDSS) and healthy individuals of similar age and sex to patients will be included in the study. The cognitive function, balance, functional exercise capacity, fatigue, mood, sleep quality will be evaluated once. Investigators will use descriptive statistics and t-tests to compare variables between groups. Investigators will examine the correlations between variables using Pearson bivariate correlations. The significance level is set at p\<0,05.
Investigators
Cagla Ozkul
research assistant
Gazi University
Eligibility Criteria
Inclusion Criteria
- •Participants who 18-65 years of age
- •MS patients who are ambulatory (Expanded Disability Status Scale score ≤ 5,5 ) in a stable phase of the disease, without relapses in the last 3 month.
Exclusion Criteria
- •Participants who have orthopedic, vision, hearing, or perception problems
Outcomes
Primary Outcomes
cognitive function
Time Frame: baseline
The Brief Repeatable Battery of Neuropsychological Tests will be used. The Brief Repeatable Battery of Neuropsychological Tests (BRB-N) consists of the selective reminding, 10/36 spatial recall, symbol digit modalities, paced auditory serial addition (PASAT) and word list generation tests.
Secondary Outcomes
- Balance(baseline)
- Mood(baseline)
- Fatigue(baseline)
- Functional exercise capacity.(baseline)
- Sleep Quality(baseline)