The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.

Active, not recruiting

• Conditions: Glaucoma
• Interventions: Other: Observational study

• Registration Number: NCT06340061
• Lead Sponsor: Henan Provincial People's Hospital

Brief Summary

The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared. Additionally, an investigation was conducted to explore the relationship between anterior chamber parameters, corneal biomechanics, and the severity of glaucoma

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-20
• Status Verified: 2024-03
• Study First Submitted: 2024-03-10
• Study First Submitted QC: 2024-03-24
• Last Update Submitted: 2024-03-24
• Study First Posted: 2024-04-01
• Last Update Posted: 2024-04-01
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Clinical diagnosis of primary glaucoma.
• Must be able to cooperate to complete the inspection.

Exclusion Criteria

• Secondary glaucoma.
• Corneal disease (E. g., keratitis, corneal scarring) that the investigator believes may affect the examination.
• trauma
• congenital eye malformations

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Treatment group	Observational study	-

Primary Outcome Measures

Name	Time	Method
VF	through study completion, an average of 2 years.	visual field. The severity of glaucoma is mainly based on the damage of the visual field
ACD	through study completion, an average of 2 years.	Anterior chamber depth. Anterior Chamber Parameters.
IOP	through study completion, an average of 2 years.	Intraocular pressure
bIOP	through study completion, an average of 2 years.	Biomechanical intraocular pressure. Corneal Biomechanics Parameters.
ACW	through study completion, an average of 2 years.	Anterior chamber width. Anterior Chamber Parameters.
SSI	through study completion, an average of 2 years.	Stress-strain index. Corneal Biomechanics Parameters.

Trial Locations

Locations (1)

Henan Provincial People's Hospital; 🇨🇳 Zhengzhou, Henan, China