Preoperative oral pregabalin 150 mg versus 300 mg in total hip arthroplasty: effects on duration of spinal anesthesia and postoperative pai

Phase 1

• Conditions: Orthopaedics; Anaesthesia

• Registration Number: PACTR202201644616894
• Lead Sponsor: Mansoura University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 129

Inclusion Criteria

A total of 129 patients scheduled to undergo total hip arthroplasty under spinal anesthesia, aged 40-60 years, and ASA I-II will be enrolled in this study.

Exclusion Criteria

Exclusion criteria will include: (1) uncooperative patient, (2) allergy or contraindication to pregabalin, (3) preoperative use of antidepressants or anticonvulsants, (4)preoperative routine use of non-steroidal anti-inflammatory drugs (NSAIDs) or opioids, (5) drug or alcohol abuse, (6) history of diabetes mellitus, (7) impaired kidney function.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be the duration of sensory and motor block

Secondary Outcome Measures

Name	Time	Method
The secondary outcome will be postoperative morphine consumption, pain score, and occurrence of any side effects.