Addition of pregabalin before surgery to intravenous lidocaine during surgery and its effect on postoperative pain and stress response
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Patients undergoing elective open abdominal surgeries
- Registration Number
- CTRI/2018/06/014406
- Lead Sponsor
- JIPMER Intramural fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 43
Inclusion Criteria
Undergoing elective open abdominal surgeries, and belonging to ASA I, II and III
Exclusion Criteria
Patients sensitive to lidocaine, those suffering from cardiovascular diseases or who had preoperative changes on ECG or Echo, patients on beta blocker or opioid drugs for other indications, patients receiving perioperative pain relief through an epidural catheter, and patients with functional bowel disorders
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain score (as measured on Visual Analogue Scale) postoperativelyTimepoint: 6 hours
- Secondary Outcome Measures
Name Time Method Incidence of postoperative nausea and vomitingTimepoint: Hours;Preoperative inflammatory markers (Total leucocyte count, interleukin 6, C-reactive protein)Timepoint: Preoperative, immediate post-op, 24 hours post-op;Time to first passage of stools and flatusTimepoint: Hours