Evaluation of the analgesic effect of preoperative pregabalin in impacted mandibular third molar surgery
Phase 3
Recruiting
- Conditions
- Postoperative pain after mandibular wisdom tooth surgery.
- Registration Number
- IRCT20240515061810N1
- Lead Sponsor
- Gorgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Individuals aged between 18 to 50 years with impacted mandibular third molars and similar degrees of mesioangular impaction.
Exclusion Criteria
Systemic diseases (e.g., osteoporosis, hyperparathyroidism, chronic kidney disease, connective tissue autoimmune diseases, diabetes, thyroid disorders, etc.).
Use of medications that may interact with pregabalin (e.g., sedatives, muscle relaxants, anxiolytics, antidepressants, anticonvulsants, oral diabetes medications, and angiotensin inhibitors).
History of alcohol addiction.
Allergy to pregabalin or related drugs
Pregnancy and lactation.
Use of analgesic or anti-inflammatory drugs within 24 hours prior to surgery.
Clinical or radiographic evidence of active oral inflammation.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method