The effects of premedication with pregabalin, diazepam or placebo on preoperative anxiety : A randomized controlled trial
Not Applicable
Completed
- Conditions
- preoperative anxietypregabalindiazepam
- Registration Number
- TCTR20190424001
- Lead Sponsor
- Department of anesthesiology, Faculty of Medicine, Prince of Songkla University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 231
Inclusion Criteria
1. Patients undergoing elective surgery at songklanagarind hospital under general anesthesia or regional anesthesia
2. Age between 18 †70 year-old
3. American Society of Anesthesiologists (ASA) classification I-II
Exclusion Criteria
1. Inability to understand Thai or to provide informed consent
2. Known pregabaline or diazepam allergy
3. Regular use of pregabalin or diazepam
4. Pregnant or breast feeding
5. Known kidney(CrCl < 60 mL/min/1.73 m2)
6. psychiatric disease
7. epilepsy
8. OSA
9. Obesity(BMI> 35kg/m2)
10. History of drug abuse
11. Risk of aspiration
12. Risk of difficult airway
13. Enrollment in other study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Preoperative anxiety the evening before surgery, before anaesthesia induction Numerical rating scale for anxiety 0-10 , STAI-state, APAIS
- Secondary Outcome Measures
Name Time Method Incident of preoperative anxiety in songklanagarind hospital the evening before surgery Incident in percentage,factor associated with preoperative anxiety all time point Correlation Analysis ,sleep quality before anaesthesia induction numerical rating scale 0-10,postoperative analgesia postoperative period at recovery room numerical rating scale 0-10