A study to note the effect of giving pregabalin before surgery on pain on patients going to have breast surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: null- patients going to undergo mastectomy
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
ASA 1 and 2 patients going to undergo mastectomy with or without axillary clearance
Exclusion Criteria
1.Patientâ??s refusal.
2.If pregabalin is contraindicated.
3.If pregabalin or gabapentin has been previously used.
4.Preexisting pain at the site where the surgical incision will be made.
5.Presence of a coexisting chronic pain syndrome.
6.A deranged renal function test.
7.A recent history of alcohol or drug abuse.
8.Patients on treatment for seizures or having heart disease.
9.Diabetic patients on pioglitazone or rosiglitazone or hypertensive patients on ACE inhibitors .
10.Patients having history of any psychiatric illness.
11.The inability to understand numerical rating score(NRS) despite previous instruction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢To study the incidence of CPSP in both the groups . <br/ ><br>â?¢To study the quality of chronic pain relief in these patients at one month and three months postoperatively. <br/ ><br>Timepoint: after 1 and 3 months of surgery
- Secondary Outcome Measures
Name Time Method â?¢To compare the quality of acute pain relief in patients taking intravenous paracetamol and per oral combination of paracetamol and ibuprofen with patients taking pregabalin along with paracetamol and combination of paracetamol and ibuprofen after mastectomy with or without axillary clearance postoperatively. <br/ ><br>â?¢To study the incidence of side effects of pregabalin on the patients. <br/ ><br>Timepoint: for 5 postoperative days after surgery