The effect of pregabalin on pain and anxiety in patients undergoing PCNL surgery

Phase 3

• Conditions: Calculus of kidney.; Calculus of kidney; N20.0

• Registration Number: IRCT20200402046915N2
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Age 18 to 60 years
The patient undergoes PCNL surgery
ASA class 1 or 2

Exclusion Criteria

Use of drugs that interact with pregabalin, including: (rosiglitazone - pioglitazone - benzodiazepines - ACEIs)
People who drink alcohol
History of psychiatric disorders including suicidal ideation and depression
History of Heart Failure
History of Renal Failure
Pregnant or lactating women

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pain. Timepoint: 2, 6, 12 and 24 hours after surgery. Method of measurement: VAS questionnaire.;Anxiety before surgery. Timepoint: 2 hours before surgery and 0.5 hours before surgery. Method of measurement: Hamilton (HAM-A) questionnaire.

Secondary Outcome Measures

Name	Time	Method
Side effects of pregabalin. Timepoint: After the surgery. Method of measurement: A checklist of pregabalin side effects will be prepared and the patient will be asked after surgery.