Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- To Healthy Volunteer
- Sponsor
- Seoul National University Bundang Hospital
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- The Change of Reaction Time Between Before and After Stimulation in Each Session (MTG, STG, Sham)
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Repetitive transcranial magnetic stimulation induced virtual lesions for aphasia.
Detailed Description
To evaluate the effect of navigated repetitive transcranial magnetic stimulation in subjects with aphasia after stroke.
Investigators
Nam-Jong Paik
Professor
Seoul National University Bundang Hospital
Eligibility Criteria
Inclusion Criteria
- •fluent in Korean
- •older than 18 years old
Exclusion Criteria
- •younger than 18 years old
- •psychotic or psychiatric problems
- •contraindications to MRI/fMRI
- •uncooperative
- •metalic implants, pacemaker or cochlear implants
- •cannot perform outcome measure-related task
- •known seizure history
Outcomes
Primary Outcomes
The Change of Reaction Time Between Before and After Stimulation in Each Session (MTG, STG, Sham)
Time Frame: change between before and after the TMS stimulation for each sessions (at session 1, session 2, session 3)
Reaction time for lexical and repetition test were measured before and after the TMS stimulation at each sessions (at session 1, session 2, session 3 over MTG/STG/Sham; MTG: middle temporal gyrus, STG: superior temporal gyrus). Response times were measured via the response pad, and spoken responses were recorded via a SV-1 Voice Key apparatus. The "reaction time post TMS - reaction time pre TMS" were used for analysis.\* Arm/Group Title Arm/Group Description Maximum length (999) Repetitive magnetic stimulation (rTMS) were applied over STG