Neurobiology of Opioid Dependence: 4 - 4
Phase 2
Withdrawn
- Conditions
- Opioid-Related Disorders
- Registration Number
- NCT00000195
- Lead Sponsor
- Yale University
- Brief Summary
The purpose of this study is to determine the effect of chronic naltrexone pre-treatment on the response to yohimbine in healthy volunteers.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Behavioral, physiological, neuroendocrine response to yohimine
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie naltrexone's effect on opioid dependence in NCT00000195?
How does naltrexone pre-treatment compare to other opioid antagonists in managing withdrawal symptoms?
Are there specific biomarkers that predict response to naltrexone in opioid-related disorders?
What adverse events are associated with chronic naltrexone use in healthy volunteers?
What combination therapies involving naltrexone show promise for treating opioid dependence?
Trial Locations
- Locations (1)
VA Connecticut Healthcare System
🇺🇸New Haven, Connecticut, United States
VA Connecticut Healthcare System🇺🇸New Haven, Connecticut, United States