MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

• Conditions: Total Joint Arthroplasty; Next Generation Sequencing; Staphylococcus Aureus

• Registration Number: NCT04574752
• Lead Sponsor: Rothman Institute Orthopaedics

Brief Summary

The aims of this study were to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening using paired nasal and groin swabs, to determine, if any, discrepancy between the diagnostic techniques and to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-30
• Status Verified: 2020-09
• Study First Submitted: 2020-09-29
• Study First Submitted QC: 2020-09-29
• Last Update Submitted: 2020-09-29
• Study First Posted: 2020-10-05
• Last Update Posted: 2020-10-05
• Primary Completion: 2021-08-30
• Study Completion: 2021-08-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 163

Inclusion Criteria

• All patients undergoing primary total knee or total hip arthroplasty at our institution will be eligible.

Exclusion Criteria

• Patients included in other prospective studies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnostic techniques to identify S. aureus in total joint replacement patients	1 day	to model the potential effect of different diagnostic techniques on S. aureus detection in orthopaedic patients.

Trial Locations

Locations (1)

Rothman Orthopaedic Institute; 🇺🇸 Philadelphia, Pennsylvania, United States