Comparison between two drug combinations in spinal anaesthesia in below umbilical surgeries

Not yet recruiting

• Conditions: Measurement and Monitoring, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2022/11/047374
• Lead Sponsor: Government Hospital

Brief Summary

Spinal anesthesia is the most preferred technique for infraumbilical surgeries. Hyperbaric Ropivacaine has been shown to produce reliable and predictable anesthesia for surgery. Fentanyl, a synthetic lipophilic opioid, and Dexmedetomidine, a new highly selective alpha 2 agonist have been used as neuraxial adjuvants in spinal anesthesia to prolong intraoperative and postoperative analgesia. This study is undertaken to investigate and compare the clinical effects of 0.75% hyperbaric ropivacaine with additives such as fentanyl and dexmedetomidine on spinal anesthesia for infraumbilical surgeries.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-11-16
• Study Start: 2022-11-20

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Patients belonging to ASA physical status Class I and Class Patients without any severe comorbid diseases.

Exclusion Criteria

• Patients having any absolute contraindications for spinal anesthesia such as patient not willing, raised intracranial pressure, severe hypovolemia, bleeding diathesis, local infection and cardiac, respiratory, and CNS diseases are excluded from the study Pregnant females.
• chronic diseases such as diabetes and hypertension Patients with body mass index >30 kg/m2 Patients shorter than 150 cm.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset of sensory blockade	1min, 2min, 3min, 4min, 5min, 6min, 7min, 8min, 9min, 10min, 30min, 60min, 90min, 120min, 150min, 180min, 210min, 240min, 270min, 300min, 330min, 360min
Maximum level of sensory blockade attained and the time taken for the same	1min, 2min, 3min, 4min, 5min, 6min, 7min, 8min, 9min, 10min, 30min, 60min, 90min, 120min, 150min, 180min, 210min, 240min, 270min, 300min, 330min, 360min
Time for two-segment sensory regression	1min, 2min, 3min, 4min, 5min, 6min, 7min, 8min, 9min, 10min, 30min, 60min, 90min, 120min, 150min, 180min, 210min, 240min, 270min, 300min, 330min, 360min
Onset and duration of motor blockade	1min, 2min, 3min, 4min, 5min, 6min, 7min, 8min, 9min, 10min, 30min, 60min, 90min, 120min, 150min, 180min, 210min, 240min, 270min, 300min, 330min, 360min
Total duration of analgesia	1min, 2min, 3min, 4min, 5min, 6min, 7min, 8min, 9min, 10min, 30min, 60min, 90min, 120min, 150min, 180min, 210min, 240min, 270min, 300min, 330min, 360min

Secondary Outcome Measures

Name	Time	Method
Hemodynamic changes, Adverse Effects	5min, 10min, 15min, 20min, 25min, 30min, 35min, 40min, 45min, 50min, 55min, 60min

Trial Locations

Locations (1)

Government Hospital Gandhi Nagar; 🇮🇳 JAMMU, & KASHMIR, India

Government Hospital Gandhi Nagar

🇮🇳JAMMU, & KASHMIR, India

Dr Supriya Shree

Principal investigator

09719153125

shreesupriya25@gmail.com