A study comparing effects of levo bupivacaine in two different concentration, in spinal anaesthesia.

Not yet recruiting

• Conditions: Diseases of the genitourinary system,

• Registration Number: CTRI/2022/03/040877
• Lead Sponsor: Sir Gangaram Hospital

Brief Summary

Spinal anaesthesia is a common and established technique for providing anaesthesia for infraumblical surgeries, i.e. surgeries below naval like haemorrhoidectomy, inguinal herniorrhaphy, transurethral retropubic prostatectomy, caesarean section or surgeries on lower limbs like debridement and amputation. In this type of anaesthesia patient is awake, does not go to sleep.It has its own benifits. The patient can be discharged from hospital on the same day.That will help the patient from extra expences and long stay in hospital.Spinal block is safe, effective and easy to perform technique.Spinal anaesthesia requires smaller dose of local anaesthetics and produces intense blockade. Levobupivacaine is an isomer, S[-] enantiomer of bupivacaine. It is less cardiotoxic and neurotoxic than bupivacaine which is commonly used in spinal anaesthesia.

We intend to study the effects of hyperbaric levobupivacaine and plain levobupivacaine in spinal anaesthesia in patients . It has better safety profile than bupivacaine and hence a better choice if drug.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-02-27
• Study Start: 2022-03-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Adult patients of either gender aged 18-60 years ASA 1-ASA 3 patients Infraumblical surgeries under spinal anaesthesia.

Exclusion Criteria

Past history of spine surgery Infective focus at site of injection Coagulopathy Obesity BMI> 30 Short height< 150 cm Unwilling patients Pregnancy Lower limb paresis History of arrhythmias.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to obtain maximum sensory block.The highest level of sensory block.Two segment regression of sensory block.The degree of maximum motor block.The end time of motor block.	Onset, every 5 minutes ,every 15 minutes, 1 hour,2 hours , 3 hours

Secondary Outcome Measures

Name	Time	Method
Heart rate changes	Peripheral oxygen saturation changes

Trial Locations

Locations (1)

Sir Gangaram Hospital, India; 🇮🇳 Central, DELHI, India

Sir Gangaram Hospital, India

🇮🇳Central, DELHI, India

DrJasmine Kumar

Principal investigator

9650799091

drjkumar3111@gmail.com