Thiol/Disulfide and Oxidative Stress

Completed

• Conditions: Severe Early Childhood Caries
• Interventions: Diagnostic Test: saliva cotton swab

• Registration Number: NCT04655859
• Lead Sponsor: Kahramanmaras Sutcu Imam University

Brief Summary

The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-10
• Primary Completion: 2020-06-10
• Study Completion: 2020-09-15
• Status Verified: 2020-11
• Study First Submitted: 2020-11-30
• Study First Submitted QC: 2020-11-30
• Last Update Submitted: 2020-11-30
• Study First Posted: 2020-12-07
• Last Update Posted: 2020-12-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 3-5 years

Exclusion Criteria

• the children with systemic illness, using anti-inflammatory drug

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
severe early childhood caries	saliva cotton swab	-
healthy children	saliva cotton swab	-

Primary Outcome Measures

Name	Time	Method
thiol/disulfide homeostasis	six months	Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.

Trial Locations

Locations (1)

Aslı Soğukpınar; 🇹🇷 Kahramanmaraş, Turkey