Effects of Inspiratory Muscle Training in Patients With Acute Decompensated Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 28
- 主要终点
- Maximal Inspiratory Pressure
研究概览
简要总结
Hospitalized patients with acute decompensated heart failure (ADHF) present a high prevalence of inspiratory muscle weakness on admission and discharge. Inspiratory muscle training has been reported as a beneficial approach in chronic heart failure. However, the effects of inspiratory muscle training in hospitalized patients with ADHF have been not known. The aim of this study is to investigate the safety, feasibility, and effects of inspiratory muscle training in hospitalized patients with ADHF.
详细描述
The participants will randomly be allocated into two groups: (1) Physical training plus inspiratory muscle training, (2) Physical training
Participants in the physical training plus inspiratory muscle training group will perform inspiratory muscle training and physical training. Inspiratory muscle training will be applied with an electronic device. Physical training will be implemented as balance, mobility, functional strength, endurance exercises. During the hospitalization, the inspiratory muscle training will be carried out twice a day with mild to moderate whereas physical training will be carried out once a day. The physical training group will perform only physical training. Physical training will be implemented as balance, mobility, functional strength, endurance exercises. During the hospitalization, physical training will be carried out once a day. For the safety and feasibility of inspiratory muscle training, data will be collected daily during the hospitalization. For effects of inspiratory muscle training, data will be collected at baseline and hospital discharge.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 45 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The management of a diagnosis of ADHF over 24 hours in a hospital setting
- •Hemodynamic stability
- •The independence of basic activities of daily life before admission
排除标准
- •Acute myocardial infarction
- •Congenital heart disease
- •Endocarditis, miyocarditis or pericarditis
- •Morbid obesity
- •Already participating in cardiac rehabilitation
结局指标
主要结局
Maximal Inspiratory Pressure
时间窗: baseline and hospital discharge, an average of 4 to 10 days
Maximal inspiratory pressure will be measured by an electronic mouth pressure device (cmH2O)
次要结局
- New York Heart Association Functional Classification(baseline and hospital discharge, an average of 4 to 10 days)
- Adverse events(During the hospitalization, daily, during an average of 4 to 10 days)
- Recruitment rate(During the hospitalization, daily, during an average of 4 to 10 days)
- Retention rate(During the hospitalization, daily, during an average of 4 to 10 days)
- Physical Performance(baseline and hospital discharge, an average of 4 to 10 days)
- Frailty(baseline and hospital discharge, an average of 4 to 10 days)
- Cardiac autonomic function(baseline and hospital discharge, an average of 4 to 10 days)
- Arterial Stiffness(baseline and hospital discharge, an average of 4 to 10 days)
- Dyspnea(baseline and hospital discharge, an average of 4 to 10 days)
- Hand Grip Strength(baseline and hospital discharge, an average of 4 to 10 days)
- Disability(baseline and hospital discharge, an average of 4 to 10 days)
- One-year mortality(one year after discharge)
- Adherence rate(During the hospitalization, daily, during an average of 4 to 10 days)
研究者
Aylin Tanriverdi
Research assistant
Dokuz Eylul University