Response to increased versus standard dose of oral Vitamin D in obese and overweight children 5 to 12 years of age.
- Conditions
- Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases
- Registration Number
- CTRI/2023/07/055191
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
overweight / obese children of age 5-12 years presenting to the pediatric OPDof cnbc delhi will be screened and included in the study if their serum 25(OH) vitamin D levelks are less than 20ng/ml
1) children with confirmed or suspected malabsorption, renal or hepatic disorders.
2) children who had received vitamin D in therapeutic doses in the last 6 months.
3) children who had received drugs that may interferev with vitamin D metabolism like anticonvulsants, steriods, chemotherapy, antitubercular, h2 blockers, and thiazide diuretics and those on any herbal or ayurvedic medicines.
4) children with any known systemic illness oer metabolic disroders known to be assiociated with obesity wither before or during study or subjects with sypmtosm s/o hypothalamic obesity like hypothyroidism, cushing syndrome etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to evaluate the rise in levels of serum 25(OH)D levels in each group from baseline to 30 days after the last dose of vitamin D.Timepoint: From baseline to 30 days post supplementation of oral Vitamin D .
- Secondary Outcome Measures
Name Time Method secondary outcome: <br/ ><br>1) to measure serum 25(OH)d levels at day 7 <br/ ><br>2)serum calcium levels post suplementation day 7 & 30 <br/ ><br>3) urinary calcium creatinine ratio levels post supplementation day 7 and day 30.Timepoint: day 7 & day 30 post supplmentation