Haemodynamic and Metabolism Response During Early Rehabilitation in Sedated Patients
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Cardiac output by cardiac ultrasonography
研究概览
简要总结
Despite several positive studies, benefits of early rehabilitation on recovery and motor performance improvement need to be demonstrate. A recent study finds that despite early rehabilitation, 1 survivor of 2 (52%) acquired an ICU weakness. The low intensity exercises applied in intensive care is common and most patients stay in bed.
Under these conditions, the optimal choice of the rehabilitation technique for bedridden patient and its intensity should be studied.
The objective of the study is to evaluate the cardiovascular and metabolic response of patients during four interventions: Passive legs mobilization, Passive cycloergometter, Quadriceps neuromuscular electrical stimulation and Functional electrical stimulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mechanical ventilation
- •Ramsay < 4
排除标准
- •Rehabilitation contraindication
- •Patient with pacemaker
- •Patient under volume assist control
- •FiO2 > 80%
- •Patient under neuromuscular blockers
- •Neurologic comorbidity
结局指标
主要结局
Cardiac output by cardiac ultrasonography
时间窗: Every 3 minutes during 10 minutes exercise
次要结局
- Expiratory volume(Continuously during ten minutes exercise)
- Muscular oxygenation of vastus lateralis muscle by Near Infrared Spectroscopy(Continuously during ten minutes exercise)
- Pulmonary artery Pressure by cardiac ultrasonography(Every 3 minutes during 10 minutes exercise)
- Respiratory rate(Continuously during ten minutes exercise)
- Tricuspid annular plane systolic excursion by cardiac ultrasonography(Every 3 minutes during 10 minutes exercise)
研究者
BOUCHRA LAMIA
MD, PhD
University Hospital, Rouen