The course of energy expenditure measured by indirect calorimetry in intensive care patients fed with high versus standard enteral protein: a substudy of the PRECISe trial

Maastricht UMC0 个研究点目标入组 400 人开始时间: 待定最近更新: 2024年2月28日

试验速览

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•Any patient admitted to the intensive care unit must meet all of the following criteria to be eligible for the PRECISe study:
•1.Adult = 18 years-old admitted to the ICU
•2.Unplanned ICU admission
•3.Invasive mechanical ventilation initiated <24 hours of ICU admission
•4.Expected ICU stay on ventilator support of = 3 days

•Any patient admitted to the Intensive Care Unit meeting one or more of the following criteria is not eligible for the PRECISe study:
•1.Contraindication for enteral nutrition
•2.Moribund or expected withholding of treatment
•3.Kidney failure with no dialysis”-code on admission
•4.Hepatic encephalopathy (West Haven 3 – 4)
•5.Body-mass index <18 kg/m²
•Additional exclusion criteria ProtEE study:
•1.Fraction of inspired oxygen (FiO2) expected to remain > 0.7 for 24 hours after admission.
•2.Positive end-expiratory pressure (PEEP) expected to remain > 12 cm H2O for 24 hours after admission.
•3.Patient is on ECMO the first 24h after admission

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