Akershus Cardiac Examination (ACE) 1950 Study

Active, not recruiting

• Conditions: Cardiovascular Diseases; Atrial Fibrillation; Mild Cognitive Impairment; Cerebrovascular Disorders; Heart Failure

• Registration Number: NCT01555411
• Lead Sponsor: Vestre Viken Hospital Trust

Brief Summary

Akershus Cardiac Examination (ACE) 1950 Study is a large, observational, prospective, longitudinal, population-based cohort study. The overall aim is to establish an extensive cardio- and cerebrovascular age cohort of elderly subjects for various longitudinal long-term follow-up studies of cardiovascular and cerebrovascular disease.

Detailed Description

Design: The Akershus Cardiac Examination (ACE) 1950 Study is a population-based, prospective, cerebro- and cardiovascular age-cohort study of all men and women born in 1950 in Akershus County, Norway.

Time schedule: Study inclusion and baseline examinations took place in the period September 2012 - May 2015.

Current status: 10-year follow-up examinations of all participants are undertaken in 2023-2025, and sub-studies are ongoing.

Study Timeline

• Study First Submitted: 2012-03-13
• Study First Submitted QC: 2012-03-13
• Study First Posted: 2012-03-15
• Study Start: 2012-09
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-06
• Last Update Posted: 2024-05-08
• Primary Completion: 2050-12-31
• Study Completion: 2050-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 3706

Inclusion Criteria

• Resident in Akershus County (as per October 2011, prior to study invitation)
• Born in the year of 1950
• Ability to consent to participation

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Outcomes related to CVD and CV-associated conditions	Maximum 35 years

Secondary Outcome Measures

Name	Time	Method
Specific CV-associated conditions, including renal, cerebrovascular, pulmonary, etc.	Maximum 35 years
Specific CV endpoints; e.g. acute myocardial infarction, heart failure, atrial fibrillation, etc.	Maximum 35 years
Specific clinical phenotypes; e.g. myocardial and arterial structure and function, lung function, etc.	Maximum 35 years

Trial Locations

Locations (2)

Akershus University Hospital; 🇳🇴 Lørenskog, Akershus, Norway

Vestre Viken HT, Baerum Hospital, Department of Medical Research; 🇳🇴 Sandvika, Akershus, Norway