Motor Performance in Parkinson's Disease After High Intensive Exercise or Deep Brain Stimulation

Not Applicable

Completed

• Conditions: Parkinson's Disease
• Interventions: Procedure: Deep Brain Stimulation; Other: High intensive antigravity locomotor exercise

• Registration Number: NCT01446549
• Lead Sponsor: University of Copenhagen

Brief Summary

The purpose of this study is (1) to provide quantitative information of the motor manifestations of Parkinson's disease and (2) to quantify the effect of high intensive antigravity locomotor exercise or Deep Brain Stimulation implantations in Parkinson's disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07
• Study First Submitted: 2011-09-29
• Study First Submitted QC: 2011-09-30
• Study First Posted: 2011-10-05
• Status Verified: 2013-09
• Primary Completion: 2013-09
• Study Completion: 2013-09
• Last Update Submitted: 2013-09-22
• Last Update Posted: 2013-09-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

• Cardiovascular disease
• Conditions that contraindicate physical exercise or the examination

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Deep Brain Stimulation	Deep Brain Stimulation	-
Locomotor Exercise	High intensive antigravity locomotor exercise	-

Primary Outcome Measures

Name	Time	Method
Change in Isometric Tremor Approximate Entropy	Change from baseline up to 16 weeks	Approximate Entropy is a metric. When used to quantify isometric tremor irregularity, information of dominant/pathological CNS oscillators can be obtained.

Trial Locations

Locations (1)

Hvidovre University Hospital; 🇩🇰 Hvidovre, Denmark