Effect Of Complete Decongestive Therapy On Carpal Tunnel Syndrome Post Upper Limb Lymphedema

Not Applicable

Not yet recruiting

• Conditions: Lymphedema
• Interventions: Other: Complete decongestive therapy; Other: Medical treatment

• Registration Number: NCT05932381
• Lead Sponsor: Cairo University

Brief Summary

this study will be conducted to investigate the therapeutic effect of complete decongestive therapy on carpal tunnel syndrome post-upper limb lymphedema.

Detailed Description

lymphedema is a chronic condition characterized by lymphatic vessel ectasia and valve dysfunction, followed by the reflux of lymphatic fluid into the interstitial space. Lymph stasis may lead to a chronic inflammatory process, resulting in adipose tissue differentiation and fibro adipose tissue deposition. One consequence of post-mastectomy lymphedema may be the development of nerve entrapments. One example is median nerve entrapment in the carpal canal, or carpal tunnel syndrome (CTS). many studies assessed the relationship of CTS as a risk factor for developing lymphedema, other studies stated the possibility of lymphedema as a potential contributor to CTS development. Complex decongestive treatment of breast cancer-related lymphoedema is an accepted strategy and is considered as an international standard for treatment. A previous review concluded that complex decongestive therapy has a positive impact on the volume of arm and quality of life in different stages of lymphedema.sixty females will be allocated randomly to two groups; first one will receive decongestive therapy and the second one will receive the routine medical treatment for ten weeks

Study Timeline

• Status Verified: 2023-06
• Study First Submitted: 2023-06-27
• Study First Submitted QC: 2023-06-27
• Last Update Submitted: 2023-06-27
• Study Start: 2023-07-05
• Study First Posted: 2023-07-06
• Last Update Posted: 2023-07-06
• Primary Completion: 2023-10-05
• Study Completion: 2023-10-05

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• Age will range between 20- 40 years.
• Only females will participate in the study.
• All patients have carpal tunnel syndrome post upper limb lymphedema.

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Exclusion Criteria

• Diabetes mellitus.
• Individuals with cardiopulmonary conditions.
• Individuals undergoing radiation therapy or chemotherapy.
• Hepatic or pancreatic diseases.
• Sensory impairment.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Complete decongestive therapy	Complete decongestive therapy	the patients will receive complete decongestive therapy twice a week for ten weeks
medical treatment	Medical treatment	the patients will receive routine medical treatment for ten weeks
Complete decongestive therapy	Medical treatment	the patients will receive complete decongestive therapy twice a week for ten weeks

Primary Outcome Measures

Name	Time	Method
hand strength	up to ten weeks	hand held dynamometer will be used for measuring the hand strength
median nerve conduction velocity	up to ten weeks	median nerve conduction velocity will be measured by electromyography device

Secondary Outcome Measures

Name	Time	Method
pain intensity	up to ten weeks	Visual analogue scale which is 100 mm horizontal line will be used for measuring pain intensity. the scale has no pain on the left side and worst pain on the right side