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临床试验/NCT05932381
NCT05932381尚未招募不适用

Effect Of Complete Decongestive Therapy On Carpal Tunnel Syndrome Post Upper Limb Lymphedema

Cairo University0 个研究点目标入组 60 人开始时间: 2023年7月5日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
主要终点
hand strength

研究概览

简要总结

this study will be conducted to investigate the therapeutic effect of complete decongestive therapy on carpal tunnel syndrome post-upper limb lymphedema.

详细描述

lymphedema is a chronic condition characterized by lymphatic vessel ectasia and valve dysfunction, followed by the reflux of lymphatic fluid into the interstitial space. Lymph stasis may lead to a chronic inflammatory process, resulting in adipose tissue differentiation and fibro adipose tissue deposition. One consequence of post-mastectomy lymphedema may be the development of nerve entrapments. One example is median nerve entrapment in the carpal canal, or carpal tunnel syndrome (CTS). many studies assessed the relationship of CTS as a risk factor for developing lymphedema, other studies stated the possibility of lymphedema as a potential contributor to CTS development. Complex decongestive treatment of breast cancer-related lymphoedema is an accepted strategy and is considered as an international standard for treatment. A previous review concluded that complex decongestive therapy has a positive impact on the volume of arm and quality of life in different stages of lymphedema.sixty females will be allocated randomly to two groups; first one will receive decongestive therapy and the second one will receive the routine medical treatment for ten weeks

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Investigator, Outcomes Assessor)

盲法说明

opaque sealed envelope

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Age will range between 20- 40 years.
  • Only females will participate in the study.
  • All patients have carpal tunnel syndrome post upper limb lymphedema.

排除标准

  • Diabetes mellitus.
  • Individuals with cardiopulmonary conditions.
  • Individuals undergoing radiation therapy or chemotherapy.
  • Hepatic or pancreatic diseases.
  • Sensory impairment.

结局指标

主要结局

hand strength

时间窗: up to ten weeks

hand held dynamometer will be used for measuring the hand strength

median nerve conduction velocity

时间窗: up to ten weeks

median nerve conduction velocity will be measured by electromyography device

次要结局

  • pain intensity(up to ten weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sara Abd Elmohsen Ali

principle investigator Sara Abd Elmohsen Ali

Cairo University

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