Comparison of bone grafts in treatment of bony defects

Not yet recruiting

Brief Summary: Primary objective1. To evaluate the clinical parameters and bone fill of bioactive calcium phospho-silicate graft in the treatment of three wall intrabony defects at different time intervals. 2. To evaluate the clinical parameters and bone fill of bioactive calcium phospho-silicate graft with enamel matrix derivative in the treatment of three wall intrabony defects at different time intervals. Secondary objective To compare the clinical parameters and bone fill of bioactive calcium phospho-silicate graft and calcium phospho-silicate graft with enamel matrix derivative in the treatment of three wall intrabony defects at different time intervals.

Recruitment & Eligibility

Inclusion Criteria

Inclusion criteria 1.
Patients in the age group of 18-45 years.
Patients with probing pocket depth > 6 mm and clinical attachment level > 8 mm.
Patients with three wall intrabony defects in mandibular posterior teeth.
Patients willing to keep appointments.
Exclusion criteria 1.
Patients on medication for systemic diseases.
Patients undergone regenerative periodontal therapy last 6 months.
Patients on antibiotics and non-steroidal anti-inflammatory analgesic therapy in last 3 months.
Test and control sites involving caries and any kind of prosthesis.
Pregnant and lactating females.
Patients with history of allergy to synthetic grafts and EMD.
Patients refusing to give consent for EMD.
Patients using any form of tobacco.

Exclusion Criteria

Inclusion criteria 1.
Patients in the age group of 18-45 years.
Patients with probing pocket depth > 6 mm and clinical attachment level > 8 mm.
Patients with three wall intrabony defects in mandibular posterior teeth.
Patients willing to keep appointments.
Exclusion criteria 1.
Patients on medication for systemic diseases.
Patients undergone regenerative periodontal therapy last 6 months.
Patients on antibiotics and non-steroidal anti-inflammatory analgesic therapy in last 3 months.
Test and control sites involving caries and any kind of prosthesis.
Pregnant and lactating females.
Patients with history of allergy to synthetic grafts and EMD.
Patients refusing to give consent for EMD.
Patients using any form of tobacco.

Primary Outcome Measures

Name	Time	Method
Primary- There is no difference seen in clinical parameters and bone fill levels in patients with or without graft placement.	Baseline, 3 month, 6 month

Secondary Outcome Measures

Name	Time	Method
Clinical parameters like gingival index, plaque index, probing depth, clinical attachment level & radiographic assessment will be done at baseline & at 6 months

Locations (1): Manav Rachna dental college
🇮🇳
Faridabad, HARYANA, India
Manav Rachna dental college
🇮🇳Faridabad, HARYANA, India
DR ANJALI BATRA
Principal investigator
9821130340
anjalibatra04@gmail.com