The investigation study on endogenous amino acids and amino acid derivatives changes following exercise.
- Conditions
- Healthy subjects
- Registration Number
- JPRN-UMIN000052868
- Lead Sponsor
- Pharma Foods International,Co.Ltd.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- Male
- Target Recruitment
- 10
Not provided
1.Individuals currently undergoing medication or outpatient treatment for any serious illness. 2.Individuals currently undergoing exercise or dietary therapy under medical supervision. 3. Individuals with current or past history of substance dependence or alcohol dependence. 4.Individuals currently undergoing outpatient treatment for mental disorders (such as depression) or sleep disorders, or with a history of past mental health disorders. 5.Individuals with irregular lifestyle rhythms due to night shifts or shift work. 6.Individuals with extremely irregular habits in diet, sleep, and other lifestyle factors. 7.Individuals practicing extreme dietary restrictions. 8.Individuals with a history of or current serious diseases, such as brain disorders, malignant tumors, immune disorders, diabetes, liver diseases (hepatitis), kidney diseases, heart diseases, thyroid disorders, adrenal disorders, and other serious metabolic disorders. 9. Individuals regularly consuming supplements containing GABA. 10.Individuals who have participated in another clinical trial (study) within the past 3 months from the date of consent or have plans to participate in another clinical trial (study) during the trial period. 11. Individuals who have donated blood or blood components exceeding 200 mL within the past 1 month or 400 mL within the past 3 months from the date of consent. 12. Individuals who find it difficult to comply with the recording requirements of various survey forms. 13. Any other individuals deemed unsuitable as participants by the trial coordinator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method (Metabolic responses to exercise) 1.Amino acids 2.Lactate 3.Amino acid derivatives * Examine time-course metabolomic changes in blood before and after exercise trials (0,60,120,180 min) * For the endurance exercise trial, blood collection will take place before exercise, 30 minutes during the exercise, and at 0, 60, 120, and 180 min after exercise.
- Secondary Outcome Measures
Name Time Method 1.Physical measurement 2.Vital signs(Blood pressure/heart rate) *During endurance exercise trial, real time heart rate is monitored for maintaining 60% heart reserve rate.