Randomized Controlled Trial to Evaluate an Optimization Procedure of Alveolar Recruitment During Transport Performed by Nurse Anesthetists in Intensive Care
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 2
- 主要终点
- Measure of the pa02/Fi02
研究概览
简要总结
Intra hospital transport of ICU patients is still at high risk of respiratory complications.We propose to determine if endotracheal tube clamping prior to disconnect ventilator allows to avoid oxygenation decrease.
详细描述
Changing respiratory support and multiples endotracheal tube disconnections may induce a loss of PEEP and finally lead to alveolar derecruitment. This study is an evaluation of a care procedure to limit the incidence of alveolar derecruitment in ventilated intubated ICU patients during transport for CT scan.
Intra hospital transport of ICU patients are performed by anesthesiologist nurses, the physician entrusts them this activity.
This is a randomized controlled study, the procedure is to clamp endotracheal tube before each disconnection from ventilator.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •intensive care patient
- •intubated, sedated, controlled assisted ventilation
- •Intra hospital transport for CT scan
- •arterial catheter
- •the patient or his trusted person consent to the study
排除标准
- •Patient Covid tests positive or Covid test results not received
- •extubated, unsedated,
- •reinforced tube
- •tracheotomy
- •pregnancy
- •guardianship
结局指标
主要结局
Measure of the pa02/Fi02
时间窗: 1 hour after the end of the transport
Evaluate the effectiveness of a procedure to avoid alveolar delisting, measured by the absence of a decrease in the PaO2/FiO2 ratio (before transport and 1 hour after return to bed) during an HIT performed by a nurse anaesthetist/caregiver team, of intubated and ventilated resuscitation patients in a controlled assisted volume.
次要结局
- length of stay(up to 28 days)
- occurrence of adverse events during the HIT(immediately after the end of the HIT)
- duration of invasive ventilation(up to 28 days)
- Assessment of the pa02(6 hours after the end of of the HIT)