Randomized Controlled Trial to Evaluate an Optimization Procedure of Alveolar Recruitment During Transport Performed by Nurse Anesthetists in Intensive Care
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Respiratory Complication
- Sponsor
- University Hospital, Montpellier
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- Measure of the pa02/Fi02
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Intra hospital transport of ICU patients is still at high risk of respiratory complications.We propose to determine if endotracheal tube clamping prior to disconnect ventilator allows to avoid oxygenation decrease.
Detailed Description
Changing respiratory support and multiples endotracheal tube disconnections may induce a loss of PEEP and finally lead to alveolar derecruitment. This study is an evaluation of a care procedure to limit the incidence of alveolar derecruitment in ventilated intubated ICU patients during transport for CT scan. Intra hospital transport of ICU patients are performed by anesthesiologist nurses, the physician entrusts them this activity. This is a randomized controlled study, the procedure is to clamp endotracheal tube before each disconnection from ventilator.
Investigators
Eligibility Criteria
Inclusion Criteria
- •intensive care patient
- •intubated, sedated, controlled assisted ventilation
- •Intra hospital transport for CT scan
- •arterial catheter
- •the patient or his trusted person consent to the study
Exclusion Criteria
- •Patient Covid tests positive or Covid test results not received
- •extubated, unsedated,
- •reinforced tube
- •tracheotomy
- •pregnancy
- •guardianship
Outcomes
Primary Outcomes
Measure of the pa02/Fi02
Time Frame: 1 hour after the end of the transport
Evaluate the effectiveness of a procedure to avoid alveolar delisting, measured by the absence of a decrease in the PaO2/FiO2 ratio (before transport and 1 hour after return to bed) during an HIT performed by a nurse anaesthetist/caregiver team, of intubated and ventilated resuscitation patients in a controlled assisted volume.
Secondary Outcomes
- length of stay(up to 28 days)
- occurrence of adverse events during the HIT(immediately after the end of the HIT)
- duration of invasive ventilation(up to 28 days)
- Assessment of the pa02(6 hours after the end of of the HIT)