Efficacy of melatonin with ibuprofen chronotherapy after periodontal surgery
Completed
- Conditions
- Chronic periodontitis,
- Registration Number
- CTRI/2023/01/048820
- Lead Sponsor
- Supriya Mishra
- Brief Summary
A randomized control double blinded cross over trial will be conducted on 75 participants to find out the efficacy of melatonin with ibuprofen chronotherapy in reducing the pain perception after periodontal surgery and compare the results with that ibuprofen chronotherapy in reducing pain perception after periodontal surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
- Systemically healthy patient having generalized periodontitis needing periodontal flap surgery.
- Patients willing to undergo flap surgery Patients willing to participate in the study.
Exclusion Criteria
- Patients with known systemic disorders and under medication for the same.
- Patients allergic to melatonin and/or ibuprofen Patients with a history of anti-inflammatory and/or antibiotic therapy over the last six months Patients with a history of periodontal therapy over the last six months Pregnant and lactating mothers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain perception will be lesser in the intervention group (melatonin with ibuprofen chronotherapy) than in the comparator groups Pain perception will be checked 24 hours, 48 hours and 72 hours after surgery.
- Secondary Outcome Measures
Name Time Method Adverse consequences after intervention therapy( melatonin with ibuprofen chronotherapy) will be lesser when compared to the comparator groups. 24 hours, 48 hours and 72 hours post surgery
Trial Locations
- Locations (1)
Bhilai dental care
🇮🇳Durg, CHHATTISGARH, India
Bhilai dental care🇮🇳Durg, CHHATTISGARH, IndiaSupriya MishraPrincipal investigator8223859339dr.supriya4@gmail.com