Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance

Not Applicable

Completed

• Conditions: Postprandial Hyperglycemia
• Interventions: Other: Beetroot; Other: Mango; Other: Blackcurrant; Other: Rose hip; Other: Glucose drink; Other: Bilberry

• Registration Number: NCT03159065
• Lead Sponsor: Lund University

Brief Summary

Consumption of polyphenol-rich fruits and vegetables may improve the postprandial glucose and insulin responses and hence promote well-being. It has previously been observed that consumption of a bilberry drink decreases the postprandial insulin demand. In the present study, the impact of probiotic fruit beverages with different polyphenol profiles on the postprandial levels of glucose and insulin, were investigated.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-09
• Primary Completion: 2014-11
• Study Completion: 2015-01
• Status Verified: 2017-05
• Study First Submitted: 2017-05-17
• Study First Submitted QC: 2017-05-17
• Study First Posted: 2017-05-18
• Last Update Submitted: 2017-05-18
• Last Update Posted: 2017-05-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Healthy, not on medication, non-allergic, individuals aged 18-65 years old, having a BMI between 20-30 kg/m2 and also maintaining stable body weight, i.e. less than 5% weight change in the last three months before the study.

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Beetroot	Beetroot	A beetroot-based based beverage with fermented oatmeal
Mango	Mango	A mango-based based beverage with fermented oatmeal
Blackcurrant	Blackcurrant	A blackcurrant-based beverage with fermented oatmeal
Rose hip	Rose hip	A rose hip-based based beverage with fermented oatmeal
Glucose drink	Glucose drink	A reference glucose drink
Bilberry	Bilberry	A bilberry-based beverage with fermented oatmeal

Primary Outcome Measures

Name	Time	Method
Efficacy of the study products on the postprandial serum insulin	Incremental area under the curve for serum insulin from 0 min up to 120 min following the ingestion of the study product	The postprandial incremental area under the curve for serum insulin

Secondary Outcome Measures

Name	Time	Method
Efficacy of the study products on the postprandial serum glucose	Incremental area under the curve for serum glucose from 0 min up to 120 min following the ingestion of the study product	The postprandial incremental area under the curve for serum glucose