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Clinical Trials/NCT05716776
NCT05716776Not yet recruitingNot Applicable

Effect of Axial Length on Peripapillary Retinal Nerve Fibre Layer (RNFL) Using Optical Coherence Tomography (OCT)

Sohag University0 sites80 target enrollmentStarted: February 2023Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
80
Primary Endpoint
Retinal nerve fibre layer (RNFL) thickness
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

the goal of this obsrevational study is to learn about retinal nerve fibres and if their numbers changed with axial length of the globe or not. the main question to answer is there is effect of long axial length on the thickness of the retinal nerve fibers participants will be asked to:

  • measure the axial length with ultrasound
  • measure the thickness of retinal nerve fibers with optical coherence tomography

Detailed Description

Aim of the work:

To investigate the effect of axial length on the peripapillary retinal nerve fiber layer.

Patients and methods Study design: Cross sectional comparative study. Location: Ophthalmology department, Sohag teaching hospital. Ethical approval: A written informed consent will be taken from all patients about the aim of the study, the nature of the planned investigation. An approval of the ethical committee of Sohag Faculty of Medicine will be fulfilled.

Methodology The study will include 80 patients healthy volunteers who underwent ophthalmologic examinations including retinal nerve fiber layer (RNFL) thickness analysis with optical coherence tomography (OCT), auto refraction, and axial length measurement.

Inclusion criteria:

Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
18 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Healthy volunteers attending the outpatient clinic for surface ocular diseases.
  • •patients who are cooperative with optical coherence tomography (OCT) device.

Exclusion Criteria

  • •Glaucoma patients.
  • •Media opacity (corneal, lens or vitreous opacity)
  • •Previous ocular surgery.
  • •Diabetic patients.
  • •Retinal diseases.

Outcomes

Primary Outcomes

Retinal nerve fibre layer (RNFL) thickness

Time Frame: average of one year

Measuring Retinal nerve fibre layer (RNFL)thickness using OCT

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Asmaa Ibrahim Mostafa

Principal Investigator, ophthalmology resident

Sohag University

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