Comparison of the effects of atropine on haemodynamics and tissue oxygenation in anaesthesia with propofol and sufentanil versus propofol and remifentanil.

Completed

• Conditions: CABG; Open Heart Surgery; 10011082

• Registration Number: NL-OMON38529
• Lead Sponsor: anesthesiologie- onderzoeksbureau

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 70

Inclusion Criteria

- Age: 18 years and older
-- Written informed consent to participate in this study.
- Elective CABG surgery performed off-pump.
- Patient and surgical procedure appropriate for treatment with either sufentanil or remifentanil.

Exclusion Criteria

- Refusal to participate in this study.
- Age: younger than 18 years.
- Pregnant.
- BMI > 35 kg/m2.
- Patients in which atropine is contra-indicated.
- Patients in which sufentanil or remifentanil at the proposed doses are contra-indicated.
- Urgent or emergency surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The change in CO (continuous measurement of the Nexfin monitor) around the<br /><br>moment of atropine administration.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The evolution of MAP, SctO2 and SptO2 around the moment of atropine<br /><br>administration.</p><br>