Prognostic value of pretreatment imaging parameters for recurrent laryngeal and hypopharyngeal carcinoma after primary radiotherapy; a retrospective study.
- Conditions
- arynx and hypopharynx carcinoma
- Registration Number
- NL-OMON24461
- Lead Sponsor
- MC Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
Patients with larynx or hypopharynx carinoma primarily treated with radiotherapy with curative intent with or without additional chemotherapy. Treated in UMC Utrecht in the period of January 2008 and March 2020. Follow-up of at least 2 years or until recurrence. Available MRI imaging of the tumor site is made within 4 weeks before the start of the radiotherapy treatment.
Exclusion Criteria
History of carcinoma at the time of diagnosis. Distant metastasis or second primary tumours at time of diagnosis.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effect of imaging variables (e.g. apparent diffusion coefficient, tumor volume, and dynamic contrast enhanced MRI variables) on treatment outcome.
- Secondary Outcome Measures
Name Time Method The effect of clinical variables (e.g. smoking status and tumor stage) on treatment outcome