Acute Immunological Effects of Exercise in Cancer Patients
Phase 2
Active, not recruiting
- Conditions
- Cancer
- Registration Number
- NCT05656651
- Lead Sponsor
- Universität Duisburg-Essen
- Brief Summary
The aim of the study is to evaluate and compare immune response to a single exercise intervention in cancer patients and healthy age-maged individuals.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Adolescents and young adults >14 years of age
- undergoing acute cancer treatment (chemotherapy)
- signed informed consent
Exclusion Criteria
- Inability to follow and implement test instructions
- medical contraindication to HIIT on cycle ergometer
- chemotherapeutic treatment 48 h prior
- Hb <8g/dl; platelets < 20,000/ul.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Number of Natural Killer Cells Change from pre Intervention to immediately after intervention and 1 hour post intervention NK cells, subgroups and innate lymphoid cells
- Secondary Outcome Measures
Name Time Method Subjective Quality of Life Once after intervention Quality of Life (EORTC QLQ-C30, questionnaire score from 0 - 100, higher score = better quality of life)
Nutritional status Once after intervention Mini Nutritional Assessment (MNA range 0 - 14 points), lower score = worse
Fatigue Once after intervention Fatigue (EORTC QLQ FA12 Fatigue questionnaire range 0 - 100, higher score = worse outcome)
Trial Locations
- Locations (1)
University Hospital Essen
🇩🇪Essen, NRW, Germany
University Hospital Essen🇩🇪Essen, NRW, Germany