Physical Activity Program and Energy Intake Control in Obese Adolescents

Not Applicable

• Conditions: Pediatric Obesity
• Interventions: Behavioral: Physical activity intervention

• Registration Number: NCT02482220
• Lead Sponsor: Université Blaise Pascal, Clermont-Ferrand

Brief Summary

Acute exercise of high intensity has been shown to induced nutritional adaptations in obese adolescents. Indeed, several studies have shown that about 30 minutes of intensive exercise (above 70% of the adolescents maximal aerobic capacities) can favor reduced-energy consumption at the following meal with no modification of their appetite feelings. Although it is suggested that chronic physical activity programs can induce energy intake modifications, this has never been clearly studied. The aim of this work is to compare different physical activity programs (low vs. high intensity programs) in terms of energy intake, appetite feelings and appetite-regulating hormones, in obese adolescents.

Detailed Description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:

* anthropometric measurements

* Body composition assessed by DXA

* Maximal aerobic test

* Blood samples (appetite-regulating hormones)

* daily energy intake assessment during a 24h intake exploration.

The adolescents recruited will then be randomly assigned to one of the two intervention groups:

- High Intensity program or moderate intensity program. Those two physical activity programs will last 4-months and will be composed of 3 to 4 exercise sessions per week. The High intensity program will consists in High intensity interval exercises starting at 70% of the adolescents' capacities at the beginning to end around 95%. The moderate intensity program will propose continuous exercises set between 50-65% VO2max.

No energy intake intervention will be performed.

By the end of the 4-months intervention, all the clinical examinations performed before the intervention will be repeated.

Study Timeline

• Study Start: 2015-06
• Study First Submitted: 2015-06-19
• Study First Submitted QC: 2015-06-25
• Study First Posted: 2015-06-26
• Status Verified: 2016-05
• Last Update Submitted: 2016-05-10
• Last Update Posted: 2016-05-11
• Primary Completion: 2017-12
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• 12 to 15 years old adolescents
• Obese according to international values for BMI
• Being registered to the national social security insurance
• no eating disorders
• no medications
• metabolic disorders

Exclusion Criteria

• metabolic disorders
• food disorders
• physical disability

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Moderate intensity	Physical activity intervention	in this group, the participants will follow a moderate intensity physical activity program (Intensity from 50 to 65% VO2max)
High intensity	Physical activity intervention	in this group, the participants will follow a high intensity physical activity program (High Intensity Interval exercise from 75 to 95% VO2max)

Primary Outcome Measures

Name	Time	Method
change in Energy intake in kcal is being assessed	energy intake will be assessed during 24h during the week before the intervention (T0) and the week after (T1)	daily energy intake will be assessed

Trial Locations

Locations (1)

AME2P Laboratory; 🇫🇷 Clermont-ferrand, Auvergne, France