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Exercise Intensity and Appetite in Adolescents

Not Applicable
Conditions
Pediatric Obesity
Interventions
Behavioral: acute exercise
Registration Number
NCT02484612
Lead Sponsor
Université Blaise Pascal, Clermont-Ferrand
Brief Summary

Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings.

Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults.

The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.

Detailed Description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:

* anthropometric measurements

* Body composition assessed by dual energy x-ray absorptiometry

* Maximal aerobic test

They will then randomly complete the following conditions:

* CON: a control day without exercise;

* HIE: an exercise day with an exercise set at 75% of the capacities

* LIE: an exercise day with an exercise set at 40% of the capacities

The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted.

Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Male
Target Recruitment
30
Inclusion Criteria
  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders
Exclusion Criteria
  • metabolic disorders
  • food disorders
  • physical disability

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Arm && Interventions
GroupInterventionDescription
Lean adolescentsacute exercise15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited
Obese adolescentsacute exercise15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited
Primary Outcome Measures
NameTimeMethod
energy intake in kcalup to 2 months

buffet meal

Secondary Outcome Measures
NameTimeMethod
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