Autologous Serum Skin Testing in Patients With Atopic Dermatitis Autologous Serum Skin Testing in Patients With Atopic Dermatitis

Completed

• Conditions: Atopic Dermatitis, Serum Skin Test

• Registration Number: NCT01238263
• Lead Sponsor: Yuzuncu Yıl University

Brief Summary

Recently, IgE-type autoantibodies against self proteins have been detected in the serum of the atopic dermatitis patients. The role of this IgE autoantibodies involved in the pathogenesis of atopic dermatitis is not known, yet. But, there may be a correlation between the severity of the disease and the serum levels of this autoantibodies. The autologous serum skin testing is applied to both atopic dermatitis patients and healthy control and the results are estimated in this study.The investigators detected 70% positive autologous serum skin testing in atopic dermatitis patients and test positivity was higher in patients with atopy history, moderately severe disease calculated by SCORAD index and high serum IgE levels.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-04
• Status Verified: 2009-05
• Primary Completion: 2010-06
• Study Completion: 2010-08
• Study First Submitted: 2010-11-09
• Study First Submitted QC: 2010-11-09
• Last Update Submitted: 2010-11-09
• Study First Posted: 2010-11-10
• Last Update Posted: 2010-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Sixty AD patients and 30 healthy individuals

Exclusion Criteria

• . The patients showing evidence of any other disease are not included to our study. No drug was allowed fourteen days prior to the test, including antihistamines and steroids.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified