The effect of soy isoflavones and kiwifruit on bone turnover, hormone levels, blood lipids and faecal microflora in menopausal women.

Not Applicable

Completed

• Conditions: Osteoporosis; Blood lipids; Musculoskeletal - Osteoporosis; Metabolic and Endocrine - Normal metabolism and endocrine development and function

• Registration Number: ACTRN12613001001785
• Lead Sponsor: Zespri International

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09-10
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Healthy post-menopausal women aged between 50-65 will be recruited.

Exclusion Criteria

Exclusion criteria are as follows: osteoporosis at the hip or spine; history of chronic renal or hepatic disease, history of hormone therapy use or breast cancer, soy allergies, and use of any other medication known to affect the skeleton or antibiotics that will affect gut microflora.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone markers urinary deoxypyridinoline, plasma C-telopeptide of Type I collagen, and serum undercarboxylated osteocalcin. [baseline and six weeks];Blood and urine daidzein, genistein and equol[Baseline and week 6]

Secondary Outcome Measures

Name	Time	Method
Blood lipids[Baseline and week 6];Blood estradiol[Baseline and week 6];Faecal microflora[Baseline and week 6 after kiwifruit consumption only. ]